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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC3
All Species:
34.55
Human Site:
T974
Identified Species:
54.29
UniProt:
Q9UQE7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQE7
NP_005436.1
1217
141542
T974
R
K
L
E
Q
C
N
T
E
L
K
K
Y
S
H
Chimpanzee
Pan troglodytes
XP_508031
1374
158072
T1131
R
K
L
E
Q
C
N
T
E
L
K
K
Y
S
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851818
1228
142683
T985
R
K
L
E
Q
C
N
T
E
L
K
K
Y
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9CW03
1217
141537
T974
R
K
L
E
Q
C
N
T
E
L
K
K
Y
S
H
Rat
Rattus norvegicus
P97690
1191
138430
K941
K
K
K
E
E
C
M
K
K
I
R
E
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512851
1238
143475
T995
R
K
L
E
Q
C
N
T
E
L
K
K
Y
S
H
Chicken
Gallus gallus
Q90988
1189
134923
S943
K
E
Y
K
W
I
A
S
E
K
E
L
F
G
Q
Frog
Xenopus laevis
O93309
1209
140704
R967
L
S
L
K
Q
L
F
R
K
L
E
Q
C
N
T
Zebra Danio
Brachydanio rerio
NP_999854
1216
141517
T974
R
K
L
E
Q
C
N
T
E
L
K
K
Y
S
H
Tiger Blowfish
Takifugu rubipres
NP_001027798
1217
141541
T974
R
K
L
E
Q
C
N
T
E
L
K
K
Y
S
H
Fruit Fly
Dros. melanogaster
NP_523374
1200
140018
T957
P
L
V
D
P
S
Y
T
R
M
S
L
K
N
I
Honey Bee
Apis mellifera
XP_393700
1202
139436
K956
P
S
H
E
V
Y
S
K
F
S
V
M
S
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202053
792
92535
T559
H
K
M
A
G
E
V
T
F
M
P
L
N
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
M915
L
E
N
E
V
T
R
M
E
M
E
H
K
N
C
Baker's Yeast
Sacchar. cerevisiae
P47037
1230
141318
T986
Q
R
L
N
D
M
N
T
E
I
S
G
L
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99
N.A.
99.9
97.2
N.A.
97.5
23.3
95.8
95.1
94.9
53.4
55.4
N.A.
40.1
Protein Similarity:
100
88.5
N.A.
99
N.A.
100
97.4
N.A.
98
46.5
97.6
97.5
97.3
73.2
72.9
N.A.
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
20
N.A.
100
6.6
20
100
100
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
60
N.A.
100
46.6
53.3
100
100
33.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
54
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
14
0
67
7
7
0
0
67
0
20
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
14
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
7
0
14
0
% G
% His:
7
0
7
0
0
0
0
0
0
0
0
7
0
0
47
% H
% Ile:
0
0
0
0
0
7
0
0
0
14
0
0
0
0
7
% I
% Lys:
14
60
7
14
0
0
0
14
14
7
47
47
14
7
7
% K
% Leu:
14
7
60
0
0
7
0
0
0
54
0
20
14
0
7
% L
% Met:
0
0
7
0
0
7
7
7
0
20
0
7
0
0
0
% M
% Asn:
0
0
7
7
0
0
54
0
0
0
0
0
7
20
7
% N
% Pro:
14
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
7
0
0
0
54
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
47
7
0
0
0
0
7
7
7
0
7
0
0
7
0
% R
% Ser:
0
14
0
0
0
7
7
7
0
7
14
0
7
47
7
% S
% Thr:
0
0
0
0
0
7
0
67
0
0
0
0
0
7
7
% T
% Val:
0
0
7
0
14
0
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
7
0
0
0
0
0
47
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _